Clinical Biochemistry-II (Practical) Notes
Subject Overview
The practical companion to Clinical Biochemistry-II, performing the glucose and insulin tolerance tests, uric acid and clearance determinations, and estimating serum acid/
Subject at a glance
1
Units
9
Topics
2
Credits
1
Infographics
Unit-wise Syllabus
1 units — click WhatsApp below to get the full notes for each
Unit 1: Dynamic tests and enzyme/hormone estimation
- Glucose tolerance test (GTT)
- insulin tolerance test (ITT)
- determination of urinary uric acid
- creatinine clearance
- urea clearance
- serum acid phosphatase
- serum alkaline phosphatase
- serum lactate dehydrogenase
- T3/T4/TSH
Creatinine clearance
(U × V) / P
U urine creatinine, V urine flow mL/min, P plasma creatinine
Normal creatinine clearance
About 90–130 mL/min
Urea clearance
(U × V) / P, using urea values
Low clearance
Reduced kidney filtration
Study guide
In this practical you perform the glucose and insulin tolerance tests, urinary uric acid, creatinine and urea clearance, serum acid and alkaline phosphatase, serum LDH and T3, T4 and TSH estimation. Take care with timing of samples in tolerance tests.
Why Clinical Biochemistry-II (Practical) Matters
Clearance tests, enzymes and thyroid profiles are major workloads of clinical biochemistry labs.
How to Prepare for Clinical Biochemistry-II (Practical)
- Plan timings for dynamic tests in advance.
- Calculate clearance values carefully with the correct units.
- Compare results with reference ranges and note the clinical meaning.
Clinical Biochemistry-II (Practical): Frequently Asked Questions
What is creatinine clearance?
It is a test that estimates how well the kidneys filter blood by comparing creatinine in blood and urine.