Unit 2: Musculoskeletal system
Human Anatomy and Physiology-I notes · PTU syllabus (BMLS203-18)
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Unit summary
Bones, joints and muscles support the body and move it. This unit covers the classification, structure and functions of the skeletal system, muscles and joints, and movements of the body.
After this unit you can
- Classify bones and describe the skeleton
- Describe the structure of bone
- Classify joints and muscles
- Describe body movements
PTU syllabus topics
- Classification
- structure and function of the skeletal system
- muscles and joints
- movements of the body
Fibrous (immovable)
Sutures of the skull
Cartilaginous (slightly movable)
Between vertebrae
Synovial: ball and socket
Shoulder, hip
Synovial: hinge
Elbow, knee
Synovial: pivot
Between atlas and axis
Topic 1
The skeletal system
- The adult skeleton has 206 bones — the axial skeleton (skull, vertebral column, ribs, sternum — 80 bones) and the appendicular skeleton (limbs and girdles — 126 bones).
- Support
- Framework of the body
- Protection
- Skull guards the brain; ribs guard heart and lungs
- Movement
- Levers for muscles
- Mineral storage
- Calcium and phosphate
- Blood formation
- Red bone marrow (haemopoiesis)
- Fat storage
- Yellow marrow
Long
Longer than wide; shaft and two ends
Femur, humerus
Short
Cube-shaped
Carpals, tarsals
Flat
Thin plates
Skull bones, sternum, ribs, scapula
Irregular
Complex shapes
Vertebrae
Sesamoid
Within tendons
Patella
Topic 2
Structure of bone
- Long bone: diaphysis (shaft) with a medullary cavity, epiphyses (ends) covered by articular cartilage, periosteum outside, endosteum inside.
- Compact bone: Haversian systems (osteons) with central canals and lamellae; spongy bone: trabeculae containing red marrow.
- Osteoblasts
- Form bone
- Osteocytes
- Mature cells in lacunae
- Osteoclasts
- Resorb bone
- Osteoprogenitor cells
- Stem cells
- Vertebral column: 33 vertebrae — 7 cervical, 12 thoracic, 5 lumbar, 5 sacral (fused), 4 coccygeal (fused).
Topic 3
Joints
Fibrous (synarthroses)
Immovable
Skull sutures
Cartilaginous (amphiarthroses)
Slightly movable
Intervertebral discs, pubic symphysis
Synovial (diarthroses)
Freely movable; joint capsule, synovial membrane and fluid, articular cartilage
Knee, shoulder, elbow
- Ball and socket
- Shoulder, hip — all directions
- Hinge
- Elbow, knee — one plane
- Pivot
- Atlas–axis — rotation
- Gliding (plane)
- Carpals
- Saddle
- Thumb carpometacarpal
- Condyloid (ellipsoid)
- Wrist
Topic 4
Muscles
- The body has over 600 skeletal muscles, attached to bones by tendons; each has an origin (fixed end) and insertion (moving end).
Appearance
Striated, multinucleated fibres
Smooth: non-striated spindle cells; cardiac: striated, branched, intercalated discs
Control
Voluntary
Involuntary
Location
Attached to skeleton
Smooth: viscera and vessels; cardiac: heart
- Contraction (sliding filament theory): a nerve impulse releases acetylcholine; calcium released from the sarcoplasmic reticulum lets myosin heads bind actin and pull, using ATP — the sarcomere shortens.
Topic 5
Movements of the body
- Flexion and extension
- Decreasing or increasing the angle — bending and straightening the elbow
- Abduction and adduction
- Away from or towards the midline
- Rotation
- Turning about an axis
- Circumduction
- Circular movement — shoulder
- Pronation and supination
- Palm down or up
- Dorsiflexion and plantar flexion
- Foot up or down
- Inversion and eversion
- Sole inward or outward
Key terms
- Axial skeleton
- Skull, vertebral column and thoracic cage
- Osteon
- Structural unit of compact bone
- Synovial joint
- Freely movable joint with a fluid-filled cavity
- Insertion
- Movable attachment of a muscle
- Sarcomere
- Contractile unit of muscle fibre
Quick revision
- 206 bones; axial 80, appendicular 126; functions.
- Long, short, flat, irregular, sesamoid bones; bone structure and cells; vertebrae.
- Fibrous, cartilaginous, synovial joints; types of synovial joints.
- Skeletal, smooth, cardiac muscle; sliding filament theory.
- Flexion, extension, abduction, adduction, rotation and other movements.
Important exam questions
Practice questions written to the PTU exam pattern for this unit's syllabus: short answers (Section A style) and long answers (Sections B and C style).
Short-answer questions
- Q1.How many bones are there in the adult skeleton?
- Q2.Give two functions of the skeleton.
- Q3.Name the cells that resorb bone.
- Q4.Give an example of a hinge joint.
- Q5.What is the sliding filament theory?
- Q6.Distinguish abduction and adduction.
Long-answer questions
- Q1.Describe the classification and functions of bones.
- Q2.Describe the structure of a long bone.
- Q3.Classify joints with examples.
- Q4.Describe muscle types and the mechanism of muscle contraction.
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